With a Wilmington, DE POTUS TFR showing up quite regularly on weekends in the Mid-Atlantic, here is a diagram with a good visual review of how to operate into/out of/through a POTUS TFR.

Most folks are aware of the location of the TFR over Wilmington at the north end of Delaware when the President goes home for the weekend. Far fewer seem to be aware that he has a beach house in Rehoboth in the southeast corner of the state just north of Maryland's Ocean City where he likes to go on summer weekends. The beach TFR extends over Ocean City Municipal Airport (OXB), which is nontowered (ditto Cape May NJ WWD and Delaware Coastal GED) so there's nobody to warn you that you're about to do something wrong as there is with the tower over at Salisbury MD (SBY). Someone made headlines a few weeks ago by taking off from OXB and flying north right through the center of the 10-ring, attracting an F-16 as a wingman.
Y'all be careful, now, hear, and check the NOTAMs carefully so you know which house he's staying at any given weekend and which Eastern Shore/PA/NJ airports are affected. And regardless, keep 121.5 up on your #2 radio or “monitor” function (if you have one) ALL the time ANYWHERE in the US National Airspace System. And it's not just the predictable TFR's like those that follow the President around. I've been in SoCal the last 10 days, and there've been pop-up firefighting TFR's all over the place.
Like they said about the 55mph speed limit back in the 70's, with NOTAM checks and monitoring 121.5 Guard, “It's not just a good idea, it's the LAW!"
Also, there seems to be quite a few “reissues” for “change in time” on these once they are published too! Check NOTAMs carefully…and timely!!!
And to the max extent practical, get VFR flight following from ATC when you're anywhere at all near a Presidential TFR. That could save you from a late time change (which seems common with President Biden) like the one just issued on today's TFR over Raleigh.
Prime example today. The Raleigh POTUS TFR has had two time changes since it was originally issued. The last a mere hour and half before the effective time.